Interleukin 5

IL5
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3VA2, 1HUL, 3QT2
Identifiers
Aliases	IL5, EDF, IL-5, TRF, interleukin 5
External IDs	OMIM: 147850; MGI: 96557; HomoloGene: 679; GeneCards: IL5; OMA:IL5 - orthologs
Gene location (Human)
Chr.	Chromosome 5 (human)
End	132,556,838 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	53,615,933 bp
RNA expression pattern
	Top expressed in
	right testis; ; left testis; ; Achilles tendon; ; right uterine tube; ; corpus callosum; ; smooth muscle tissue; ; granulocyte; ; right ovary; ; right coronary artery; ; metanephros;
	Top expressed in
	embryo; ; perirhinal cortex; ; esophagus; ; entorhinal cortex; ; CA3 field; ; medulla oblongata; ; thymus; ; primary motor cortex;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	interleukin-5 receptor binding; protein binding; growth factor activity; protein tyrosine kinase activity; cytokine activity;
Cellular component	extracellular region; intracellular anatomical structure; extracellular space;
Biological process	positive regulation of DNA-binding transcription factor activity; positive regulation of podosome assembly; MAPK cascade; positive regulation of transcription, DNA-templated; immune response; positive regulation of cell population proliferation; positive regulation of eosinophil differentiation; positive regulation of peptidyl-tyrosine phosphorylation; inflammatory response; positive regulation of receptor signaling pathway via JAK-STAT; peptidyl-tyrosine phosphorylation; positive regulation of B cell proliferation; regulation of signaling receptor activity; cytokine-mediated signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	3567
	16191
	ENSG00000113525
	ENSMUSG00000036117
	P05113
	P04401
	NM_000879
	NM_010558
	NP_000870
	NP_034688
	Wikidata
View/Edit Human	View/Edit Mouse

Interleukin 5 (IL-5) is an interleukin produced by type-2 T helper cells and mast cells.

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000113525 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000036117 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000113525 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000036117 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

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